To improve CoQ10 absorption, it is essential to take it with meals that contain fats, as CoQ10 is a fat-soluble compound. Fat in the diet helps the body dissolve and absorb CoQ10 more efficiently, increasing its bioavailability. Without fat, the absorption rate of CoQ10 can be significantly reduced, which may limit its effectiveness. Therefore, it is recommended to pair CoQ10 supplements with meals rich in healthy fats, such as avocados, nuts, olive oil, or fatty fish, to enhance the absorption and maximize its benefits for your health.